Beta-Glucosidase

Product Description

Beta-Glucosidase is a highly strategic enzyme that functions as an "in-situ activator" for advanced brightening formulations. Its mechanism is precise: it enzymatically cleaves beta-D-glucosyl moieties from precursor ingredients. Its most powerful application is converting stable, common glucosides—such as **Arbutin**—into their highly active, but otherwise unstable or restricted, aglycone forms. Specifically, it can release Hydroquinone from Arbutin directly on the skin, offering a "pro-drug" strategy. This allows B2B manufacturers to leverage the gold-standard efficacy of Hydroquinone via a sophisticated, controlled micro-dosing approach, bypassing the severe stability and regulatory issues of the active itself.

Product Uses

This enzyme is a high-technology ingredient intended for manufacturers developing cutting-edge, "next-generation" brightening and hyperpigmentation products. It is **exclusively** co-formulated with its specific glucoside substrates, most notably **Arbutin** (Alpha or Beta). This two-part system is the core of high-performance spot correctors, intensive brightening serums, and anti-melasma treatments. It can also be used to activate other plant-derived glucosides (e.g., Salicin into Salicylic Acid) for gentle exfoliation or anti-inflammatory effects, making it a versatile tool for advanced R&D labs.

Formulation Suggestions

Beta-Glucosidase is a protein enzyme and must be added during the cool-down phase (below 50°C / 122°F). **It is completely inactive without its substrate.** It **must** be formulated in conjunction with a glucoside, such as **Arbutin**, to have any function. The enzyme performs optimally in an acidic environment, with a final product pH between 4.5 and 6.0 being ideal for activity. Stability is highest in anhydrous powder formats. In aqueous solutions, a robust preservative system is essential. Our recommendations are for reference only; please follow the advice of your formulator for actual production.

Product Specification

• INCI Name: Beta-Glucosidase
• Synonyms: Gentiobiase, Cellobiase, Beta-D-glucoside glucohydrolase
• CAS No.: 9001-22-3
• Molecular Formula: Complex Polypeptide
• Appearance: White to off-white powder
• Purity: ≥98%
• Solubility: Soluble in water, insoluble in ethanol.
• Stability: Stable as dry powder. Heat sensitive (avoid >55°C). Optimal activity at acidic pH (4.5-6.0).
• Properties: Enzyme, Bio-converter, Brightening (indirect), Activator
• Origin: China