Cyanocobalamin (B12)

Product Description

This cosmetic-grade Cyanocobalamin (Vitamin B12) is synthesized and released under audited bulk supply with batch-matched COA documentation, delivering high-purity cobalamin for direct factory procurement in aqueous serums, ampoules, and scalp tonics.

As a cobalt-centred corrin complex, it functions as a methylation and cellular energy cofactor at low use levels, supporting vitality, barrier recovery, and redness modulation in water-soluble matrices vulnerable to light, pH shift, and oxidation.

Unlike oil-phase retinoids, cyanocobalamin integrates efficiently into multivitamin essences and leave-on hair treatments, where refrigerated B2B supply and UV-protective packaging differentiate professional sourcing from consumer vitamin blends.

Product Specification

• INCI Name: CYANOCOBALAMIN
• CAS No.: 68-19-9
• Appearance: Dark red crystalline powder or deep red granules (Typical)
• Solubility: Soluble in water; practically insoluble in oils and ethanol (Typical)
• Suggested pH: Stable pH 4.5–6.5; avoid strong alkalinity and UV (Typical)
• Assay Method: UV spectrophotometry at 361 nm or HPLC (Typical)
• Shelf Life: 24 months sealed at 2–8°C (Typical)
• Standard Packaging: 100 g / 1 kg amber-lined containers (Typical)
• Storage: Refrigerated 2–8°C; protect from light, moisture, and oxidation (Typical)
• Regulatory Status: Listed in EU CosIng as CYANOCOBALAMIN; skin conditioning function (Typical)
• Quality & Testing: Lot COA: assay, moisture, heavy metals, microbial limits (Typical)
• Compliance Note: For cosmetic use only. Light-sensitive; use opaque packaging and verify regional vitamin claim limits (Typical).

Key Benefits & Applications

Supports cofactor-driven vitality, barrier recovery, and soothing performance in aqueous skincare and scalp systems.

• Cobalamin Cofactor Support for Cellular Energy in Aqueous Serums and Ampoules
• Cell Turnover Support in Multivitamin Brightening and Repair Systems
• Scalp Follicle Nourishment in Leave-On Hair Tonics and Scalp Serums
• Skin Barrier Recovery in Post-Treatment Essences and Sensitive-Skin Creams
• Anti-Inflammatory Redness Modulation in Soothing Repair Formulations

Formulation Guidelines

Typical aqueous-phase guidance for light-sensitive Cyanocobalamin in serum and scalp applications below.

• Use 0.001–0.05% w/w in facial serums; up to 0.1% in scalp tonics (Typical).
• Dissolve in aqueous phase; add below 40°C to preserve cobalamin integrity.
• Stable pH 4.5–6.5; avoid strong alkalis, peroxides, and prolonged UV exposure.
• Package in amber or opaque containers; nitrogen blanket recommended for bulk storage.
• Avoid unbuffered high-level ascorbic acid combinations without dedicated stabilization.
• Synergy: Formulators often co-add Niacinamide at 2–5% with cyanocobalamin in energizing facial ampoules.