Dihydromyricetin

Product Description

Dihydromyricetin (also known as Ampelopsin) is a high-performance flavonoid, naturally sourced from Vine Tea, offering a multi-pathway solution for oily and blemish-prone skin. Its primary value lies in its unique and scientifically-backed ability to regulate sebum production by inhibiting the 5α-reductase enzyme, helping to reduce surface oiliness and minimize the appearance of pores. In addition to its powerful sebum-regulating action, Dihydromyricetin is a potent antioxidant and anti-inflammatory agent, protecting the skin from environmental damage while soothing the redness and irritation often associated with breakouts. For brands developing sophisticated, effective, and natural-origin products for oily, combination, and acne-prone skin, our high-purity Dihydromyricetin is the key to creating a balanced, clear, and healthy-looking complexion.

Product Uses

• Oily & Acne-Prone Skincare: The hero active in mattifying lotions, sebum-control serums, pore-refining toners, and targeted treatments for acne-prone skin.
• Scalp Care: A key ingredient in balancing shampoos and scalp treatments designed to regulate sebum production, reduce oiliness, and maintain a healthy scalp environment.
• Protective & Anti-Pollution Formulas: Used in daily-wear products for oily/combination skin to provide a powerful antioxidant shield against free radical damage.
• Men's Skincare: An excellent ingredient for men's skincare lines targeting concerns related to excess oil and blemishes.

Formulation Suggestions

Recommended dosage: 0.1% - 1.0%.
The primary formulation consideration for Dihydromyricetin is its limited solubility in cold water. We recommend creating a pre-mix by dissolving the powder in a suitable co-solvent like Propanediol, Butylene Glycol, or Ethanol before adding to the formula. To prevent oxidation and potential discoloration, it is essential to formulate at an acidic pH (ideally 4.0 - 6.0), incorporate a chelating agent (e.g., Disodium EDTA), and add the active during the cool-down phase of production. The use of UV-protective packaging is also recommended to ensure long-term stability.

Our advice is for reference only. Please follow the recommendations of your formulator for actual production.

Product Specification

• INCI Name: Dihydromyricetin
• Synonyms: Ampelopsin
• CAS No.: 27200-12-0
• Molecular Formula: C₁₅H₁₂O₈
• Appearance: White to light yellow fine powder
• Purity: ≥98% (by HPLC)
• Solubility: Soluble in ethanol, acetone, and hot water. Slightly soluble in cold water.
• Stability: Sensitive to light, heat, and high pH. Best formulated in protected, slightly acidic systems.
• Properties: Sebum Control (5α-reductase Inhibitor), Potent Antioxidant, Anti-inflammatory, Skin Brightening.
• Origin: China