Dipeptide-15

Product Description

Our direct factory supply delivers high-purity Dipeptide-15 (INCI: DIPEPTIDE-15), the synthetic Gly-Gly diglycine peptide with HPLC-verified purity and batch-level COA traceability for reliable bulk procurement.

As the smallest dipeptide at 132 Da, this zwitterionic glycine dimer functions as a CosIng-listed skin and hair conditioning agent, supporting aqueous moisture retention and tolerance within pH 5.0–7.5 formulation windows.

Formulators value Gly-Gly for compact peptide conditioning in essences, barrier serums, and hair treatments—offering glycine-aligned matrix support without the cost or stability trade-offs of longer signal peptides.

Product Specification

• INCI Name: DIPEPTIDE-15
• CAS No.: 556-50-3
• Sequence: Gly-Gly
• Molecular Formula: C4H8N2O3
• Purity (HPLC): ≥98% (Typical)
• Extraction Ratio: N/A — synthetic peptide (Typical)
• Appearance: White to off-white crystalline powder
• Solubility: Freely soluble in water; sparingly in ethanol (Typical)
• Suggested pH: 5.0–7.5 in finished formulas (Typical)
• Assay Method: HPLC-UV vs reference standard (Typical)
• Shelf Life: 24 months sealed, stored at ≤25°C (Typical)
• Standard Packaging: 1 kg / 25 kg foil-lined drums
• Storage: Cool, dry place; protect from light and moisture
• Regulatory Status: Listed in CosIng as DIPEPTIDE-15; skin and hair conditioning
• Quality & Testing: HPLC purity, water content, heavy metals per Typical COA limits
• Compliance Note: For cosmetic use only; not for injectable or dietary applications

Key Benefits & Applications

Dipeptide-15 (Gly-Gly) delivers compact dipeptide conditioning for skin barrier support, hydration systems, and hair care across B2B beauty lines.

• Skin Conditioning: Supports stratum corneum softness and moisture balance as a CosIng-listed conditioning agent.
• Glycine Matrix Support: Supplies glycine-rich building blocks associated with collagen-dense dermal structure.
• Humectant Activity: Small 132 Da structure aids aqueous retention in serums and essence formulations.
• Barrier Tolerance: Zwitterionic profile supports calm, tolerant skin feel in sensitive-skin toner systems.
• Hair Cuticle Conditioning: Deposits on keratin surfaces in rinse-off and leave-on conditioner systems.

Formulation Guidelines

Use Dipeptide-15 in water-rich systems where compact glycine dipeptide conditioning is required without destabilizing larger peptide actives.

• Add 0.5–2.0% w/w in serums and toners; pre-dissolve fully in the water phase before emulsification.
• Maintain pH 5.0–7.5; avoid prolonged hot processing above pH 8.0 to preserve peptide integrity.
• Compatible with glycols, panthenol, and niacinamide; patch-test with strong organic acids.
• Add below 60°C in the cool-down phase when co-formulated with heat-sensitive actives.
• Suitable for essences, barrier creams, and hair conditioners targeting conditioning and hydration.
• Synergy: Layer Hyaluronic Acid under Gly-Gly at 1–3% in pH 5.5 essences for stacked humectant conditioning.