Glutathione Peroxidase

Product Description

Glutathione Peroxidase (GPx) is an indispensable selenoenzyme that completes the skin's core antioxidant defense network. While SOD and Catalase neutralize primary water-soluble threats, GPx performs a unique and critical function: it is the only enzyme that can neutralize highly destructive **Lipid Peroxides (LOOH)**. These peroxides form when cell membranes and sebum (skin oils) are attacked by free radicals. Unchecked, lipid peroxidation leads directly to cell damage, inflammation, and visible aging. For B2B manufacturers, GPx is the ultimate "finishing" enzyme, offering total protection by stopping the damage cascade at the lipid level, which other antioxidants cannot address.

Product Uses

GPx's specialized ability to target lipid peroxidation makes it a strategic active for advanced, high-performance formulations. It is essential for "anti-pollution" and "UV-defense" products, where it protects cell membranes from degradation. Critically, it is a key ingredient for **anti-acne and oily skin** formulations, as it helps prevent the sebum (lipid) oxidation that leads to comedones and inflammation. It is also used in high-end anti-aging serums and sensitive skin treatments to stop the inflammatory cycle caused by peroxidized lipids, protecting the integrity of the skin barrier.

Formulation Suggestions

GPx is a delicate enzyme that requires precise formulation. It must be added during the final cool-down phase, with temperatures kept strictly below 40°C (104°F). **Crucially, GPx is a catalyst that *consumes* Glutathione (GSH) as its fuel.** To be effective, this enzyme **must** be formulated in conjunction with **Glutathione (GSH)**. Without its GSH cofactor, the enzyme will have no activity in the final product. The optimal pH range is 6.5 - 8.0. Encapsulation is highly recommended for enhancing stability and delivery. Our recommendations are for reference only; please follow the advice of your formulator for actual production.

Product Specification

• INCI Name: Glutathione Peroxidase
• Synonyms: GPx
• CAS No.: 9013-66-5
• Molecular Formula: Metalloenzyme (Selenoenzyme)
• Appearance: White to off-white powder
• Purity: ≥98%
• Solubility: Soluble in water. Insoluble in oils and ethanol.
• Stability: Stable as dry powder. Highly sensitive to heat (>45°C). Requires Glutathione (GSH) as a cofactor for activity.
• Properties: Antioxidant (Lipid Peroxide Neutralizer), Anti-inflammatory, Cell-protecting
• Origin: China