Hydroxypropyl Chitosan

Product Description

Hydroxypropyl Chitosan (HPCH) is a premium, chemically modified derivative of chitin designed to overcome the solubility limitations of standard chitosan. While generic chitosan requires an acidic medium for dissolution, HPCH is fully soluble in water and hydro-alcoholic mixtures at neutral pH. This unique solubility profile transforms it into a high-performance biopolymer for cosmetic applications. It forms a transparent, flexible, and "breathable" film on the skin and nails, which acts as an intelligent delivery system for active ingredients. Its molecular structure allows it to interact with keratin, providing structural reinforcement. For B2B formulators, HPCH represents the ideal bridge between "natural origin" demands and "high-tech" performance, offering a biodegradable alternative to synthetic film-formers like acrylates.

Product Uses

HPCH is widely recognized as the gold-standard vehicle for **nail care formulations**. It is extensively used in medicated nail lacquers, hardening treatments, and antifungal delivery systems due to its ability to penetrate the nail plate and carry actives deep into the keratin matrix. In **hair care**, it functions as a natural styling agent in gels and sprays, offering hold and frizz control without the flaking associated with PVP. Additionally, its film-forming capability makes it valuable in **skin barrier repair** creams and "liquid patch" products, where it protects compromised skin while maintaining moisture balance through its hydro-retentive properties.

Formulation Suggestions

Hydroxypropyl Chitosan is easy to handle compared to unmodified chitosan. It can be dissolved directly in water or water/ethanol mixtures without the need for acidification (no acetic acid required). It tolerates high alcohol concentrations (up to 70%), making it perfect for quick-drying nail and hair formulations. While it is more compatible than cationic chitosan, it still carries a weak positive charge; therefore, compatibility testing with high concentrations of strong anionic surfactants (like SLS) is recommended to prevent precipitation. Recommended usage levels range from 0.1% to 1.0% for skin/hair care and up to 5.0% for specialized nail treatments. Our recommendations are for reference only; please follow the advice of your formulator for actual production.

Product Specification

• INCI Name: Hydroxypropyl Chitosan
• Synonyms: HPCH, 2-Hydroxypropyl Chitosan
• CAS No.: 84069-44-3
• Molecular Formula: Modified Polysaccharide
• Appearance: White to pale yellow powder
• Purity: ≥95% (Deacetylation Degree >85%)
• Solubility: Soluble in water and hydro-alcoholic solutions.
• Stability: Stable in neutral pH. Heat stable up to 60°C.
• Properties: Film-forming, Carrier System, Breathable Barrier, Hair Conditioning
• Origin: China