Hydroxypyridinone

Product Description

Hydroxypyridinone is a high-performance multifunctional active ingredient primarily valued for its exceptional metal-chelating properties and broad-spectrum antimicrobial activity. In the cosmetic industry, it is widely utilized as a stabilizer to prevent the oxidative degradation of sensitive actives and as a potent anti-dandruff and anti-acne agent. Its unique hydroxamic acid-like structure allows it to bind effectively with transition metals (such as iron and copper), thereby inhibiting radical-induced spoilage and disrupting the metabolic processes of problematic microorganisms like Malassezia furfur. This ingredient is a commercially vital asset for B2B formulators focused on high-stability dermo-cosmetic and professional hair care solutions.

Product Specification

• INCI Name: Hydroxypyridinone (Commonly referred to as 2-Hydroxypyridine-N-oxide)
• CAS No.: 822-89-9 / 1121-30-8
• Chemical Name: 1,2-Dihydro-1-hydroxy-2-pyridinone
• Product Type: Chelating Agent / Antimicrobial / Anti-dandruff
• Appearance: White to off-white crystalline powder
• Purity (HPLC): ≥ 99.0%
• Solubility: Soluble in water and ethanol; sparingly soluble in non-polar solvents.

Key Benefits & Applications

• Powerful Chelating Efficacy: Superior ability to sequester metallic ions, preventing product discoloration, rancidity, and the degradation of fragile actives like Vitamin C or Retinol.
• Targeted Antimicrobial Action: Highly effective against fungi and bacteria responsible for scalp irritation and skin blemishes, making it a key component in "clear skin" formulations.
• Enhanced Formula Stability: Acts as a secondary antioxidant by neutralizing metal-catalyzed oxidation, significantly extending the shelf life of complex emulsions.
• Gentle Performance: Offers a more stable and less irritating alternative to traditional chelating agents in sensitive skin applications.
• Applications: Professional anti-dandruff shampoos, acne-prone skin treatments, high-potency antioxidant serums, and preservative-boosting systems.

Formulation Guidelines

• Suggested Dosage: 0.1% – 1.0% (Used at lower levels as a stabilizer, and higher levels as a primary active).
• pH Stability: Maintains maximum activity within a pH range of 4.0 – 8.0; stable in both acidic and slightly alkaline environments.
• Processing: Add to the water phase during the early stages of mixing. It is heat stable and can be incorporated during both hot and cold processes.
• Compatibility: Excellent compatibility with anionic and non-ionic surfactants. Use caution when formulating with high concentrations of cationic polymers.
• Synergy: Combine with Ascorbyl Glucoside (AA2G) to leverage its powerful chelating effect, which prevents metal-catalyzed oxidation and ensures the color stability and potency of Vitamin C derivatives.