Methyl Diisopropyl Propionamide

Product Description

Our high-purity Methyl Diisopropyl Propionamide (MDPP) is manufactured under ISO-aligned controls with batch COA traceability, supplying cosmetic formulators direct factory pricing and flexible kilogram-to-tonne bulk volumes for aqueous and hydroalcoholic systems.

This synthetic TRPM8-linked cooling sensate delivers an immediate, long-lasting refresh without the strong mint odor of menthol—activating trigeminal cooling pathways suited to after-sun mists, post-shave balms, scalp tonics, and sport body-care lines.

Unlike menthol crystals or high-volatility mint oils, this CosIng-listed propionamide suits low-fragrance, sensitive-skin, and menthol-free portfolios where formulators want GC-verified assay and direct factory supply.

Product Specification

• INCI Name: Methyl Diisopropyl Propionamide
• CAS No.: 163609-50-7
• Appearance: Clear, colorless to pale yellow liquid (Typical)
• Solubility: Soluble in ethanol and propylene glycol; partially soluble in water (Typical)
• Suggested pH: Stable across typical formulation pH 4–8 (Typical)
• Assay Method: GC purity assay (Typical)
• Shelf Life: 24 months sealed, below 25°C (Typical)
• Standard Packaging: 1 kg / 25 kg
• Storage: Keep sealed, cool, dry, and away from strong oxidizers (Typical)
• Regulatory Status: Listed in CosIng as Methyl Diisopropyl Propionamide; INCI recognized
• Quality & Testing: Typical COA covers GC assay, moisture, and heavy metals
• Compliance Note: For cosmetic use only; may cause cooling sensation—patch-test sensitive-skin and eye-area formulas

Key Benefits & Applications

Methyl Diisopropyl Propionamide supports instant cooling, soothing, and after-sun comfort claims through low-odor trigeminal sensate activity suited to body, scalp, and sensitive-skin formulators.

• Instant Cooling Sensation: Activates TRPM8-linked trigeminal pathways for immediate refresh in mists, gels, and lightweight emulsions.
• Soothing & Calming: Delivers counter-irritant cooling comfort in post-shave balms and sensitive-skin daily-care systems.
• Itch Relief: Cooling sensation helps mask itch perception in irritation-prone body and scalp care formulas.
• Scalp Soothing: Refreshes and calms the scalp in invigorating yet non-stinging tonics and pre-shampoo treatments.
• After-Sun Repair: Provides cooling relief in post-UV exposure body mists and after-sun gel formulations.
• Body Care Refresh: Supports sport and post-workout cooling body lotions and shower-off refresh systems.

Formulation Guidelines

Introduce MDPP in cool-process aqueous or hydroalcoholic phases; start at low levels and screen sensory intensity before scale-up.

• Suggested use level: 0.05–0.3% w/w for facial and scalp; up to 0.5% in body care (Typical).
• Processing: Add below 40°C to water, ethanol, or propylene glycol phases; avoid prolonged high-heat exposure.
• pH window: Stable pH 4–8; compatible with most preservative and surfactant systems (Typical).
• Compatibility: Works with panthenol and allantoin; avoid stacking multiple high-intensity cooling agents without sensory testing.
• Sensory note: Low odor vs menthol; intensity builds with level—cap eye-area and lip-product use accordingly.
• Synergy: Panthenol extends post-UV comfort when paired with methyl diisopropyl propionamide in cooling after-sun mists at 0.1–0.3%.