N-Prolyl Palmitoyl Tripeptide-56 Acetate

Product Description

N-Prolyl Palmitoyl Tripeptide-56 Acetate is a next-generation biomimetic lipopeptide widely recognized in the cosmetic industry as the active technology behind Matrixyl Morphomics®. Manufactured under strict quality control standards, our high-purity material is supplied directly from the factory to ensure consistent quality, traceability, and competitive wholesale pricing.

This advanced peptide is designed to support extracellular matrix remodeling by stimulating the synthesis of collagen types I, III, IV, and VI, as well as fibronectin. Studies suggest that it can help activate FOXO-mediated cellular defense pathways and enhance sestrin expression, supporting skin resilience against environmental and age-related stress. Through continuous application, the peptide contributes to improved skin density, firmness, and visible wrinkle reduction.

As consumer demand shifts toward clinically inspired anti-aging formulations, N-Prolyl Palmitoyl Tripeptide-56 Acetate has become a preferred active ingredient for premium serums, creams, and eye care products. Its excellent stability and compatibility with modern cosmetic systems make it a valuable solution for brands developing high-performance age-defying skincare.

Product Specification

• INCI Name: N-Prolyl Palmitoyl Tripeptide-56 Acetate
• Sequence: Palmitoyl-Pro-Xxx-Xxx Acetate (Typical Cosmetic Peptide Structure)
• Molecular Formula: Suggested Proprietary Peptide Complex
• Purity (HPLC): ≥99%
• Appearance: White to Off-White Powder
• Solubility: Soluble in Ethanol and Oil-Based Systems; Slightly Soluble in Water
• Suggested pH: 4.0–6.0
• Storage: Store at 2–8°C in a Dry, Light-Protected Environment
• Origin: China

Key Benefits & Applications

N-Prolyl Palmitoyl Tripeptide-56 Acetate is an advanced anti-aging peptide developed for formulations targeting visible signs of skin aging and loss of structural integrity.

• Collagen Stimulation: Promotes the production of collagen I, III, IV, and VI to support dermal density.
• Extracellular Matrix Remodeling: Enhances fibronectin synthesis for improved skin architecture.
• Expression Line Reduction: Helps visibly reduce frown lines, marionette lines, nasolabial folds, and crow’s feet.
• Skin Firmness Improvement: Supports tighter and more resilient skin appearance.
• Cellular Protection Support: Associated with FOXO pathway activation and sestrin synthesis.
• Anti-Photoaging Care: Suitable for mature, stressed, and environmentally exposed skin.
• Premium Anti-Aging Products: Ideal for serums, creams, eye treatments, facial masks, and professional skincare systems.

Formulation Guidelines

N-Prolyl Palmitoyl Tripeptide-56 Acetate is typically incorporated into advanced anti-aging formulations designed to improve skin firmness and reduce visible wrinkles.

• Recommended Dosage: 0.01%–0.05% depending on formulation objectives.
• Addition Phase: Add during the cooling stage below 40°C to preserve peptide activity.
• Recommended Systems: O/W emulsions, anti-aging serums, eye creams, and concentrated treatment products.
• Suggested pH Range: Maintain between pH 4.0 and 6.0 for optimal stability.
• Compatibility: Compatible with niacinamide, hyaluronic acid, ceramides, peptides, and vitamin C derivatives.
• Storage Recommendation: Protect from excessive heat, moisture, and direct sunlight during manufacturing and storage.
• Synergy: Combine with Palmitoyl Hexapeptide-12 for enhanced collagen support and visible wrinkle reduction.