Naringinase

Product Description

Naringinase is an innovative enzyme complex that functions as a high-tech "bio-converter" for advanced cosmetic formulations. Its purpose is not to act on the skin directly, but to activate other ingredients. Specifically, it is designed to be paired with the stable precursor Naringin (found in grapefruit). Naringinase enzymatically converts Naringin into its highly potent—but otherwise unstable and insoluble—aglycone form: **Naringenin**. This "on-site" bio-conversion allows formulators to harness the powerful brightening (tyrosinase-inhibiting) and anti-inflammatory benefits of Naringenin, bypassing its severe formulation challenges. For B2B manufacturers, this two-part system represents a cutting-edge, "pro-drug" strategy to deliver high-efficacy actives.

Product Uses

Naringinase is a strategic ingredient for manufacturers developing sophisticated, technology-driven skincare. It is exclusively used in formulations that also contain its substrate, **Naringin** (or Naringin-rich extracts like Grapefruit Extract). This system is ideal for high-performance **brightening serums**, "anti-sallowness" toners, and spot-correcting treatments, where the released Naringenin provides potent tyrosinase inhibition. It is also highly effective in **anti-inflammatory and soothing** products for sensitive or stressed skin, as Naringenin is a powerful suppressor of pro-inflammatory pathways.

Formulation Suggestions

Naringinase is an enzyme and must be added during the cool-down phase (below 50°C / 122°F). **Crucially, this enzyme is inactive without its substrate.** It **must** be co-formulated with **Naringin** to function. Naringinase exhibits its optimal activity in a highly acidic environment (pH 3.5 - 5.0), which is ideal for skin application and aligns well with many alpha-hydroxy acid (AHA) formulas. It is most stable in anhydrous (water-free) powder formats. Our recommendations are for reference only; please follow the advice of your formulator for actual production.

Product Specification

• INCI Name: Naringinase
• Synonyms: Naringin hydrolase, Naringinase complex
• CAS No.: 9068-31-9
• Molecular Formula: Enzyme Complex
• Appearance: Off-white to light tan powder
• Purity: ≥98%
• Solubility: Soluble in water, insoluble in ethanol.
• Stability: Stable as dry powder. Heat sensitive (avoid >60°C). Optimal activity at acidic pH (3.5-5.0).
• Properties: Enzyme, Bio-converter, Brightening (indirect), Anti-inflammatory (indirect)
• Origin: China