Oroxylin A

Product Description

As a dedicated wholesale supplier of functional botanical actives and high-performance flavonoids, GSS offers High Purity Oroxylin A at factory-direct prices. Extracted from Oroxylum indicum, this premium flavonoid is a multi-functional active engineered to mitigate the "digital stress" of modern environments. Its molecular mechanism centers on the potent modulation of inflammatory cytokines and the neutralisation of reactive oxygen species (ROS). Oroxylin A is specifically valued in the B2B market for its ability to shield the skin from HEV (blue light) and UV-induced oxidative damage. We provide high-purity crystalline powder in bulk, supporting the development of resilient, science-backed urban defense skincare lines.

Product Specification

• INCI Name: Oroxylin A
• Chemical Name: 5,7-Dihydroxy-6-methoxyflavone (6-Methoxybaicalein)
• CAS No.: 29548-34-9
• Molecular Formula: C16H12O5
• Molecular Weight: 284.26 g/mol
• Appearance: Yellow crystalline powder
• Purity (Assay): ≥98.0% (HPLC)
• Solubility: Soluble in ethanol and glycols (e.g., Propanediol); insoluble in water
• Stability: Stable in solid form; in formulations, protect from strong light and avoid high pH environments to prevent discoloration
• Grade: Cosmetic Grade
• Origin: China (Direct Factory Supply)

Key Benefits & Applications

• Digital & HEV Shielding: Acts as a high-bioavailability antioxidant that specifically mitigates the oxidative stress and mitochondrial damage caused by blue light exposure from digital screens.
• Advanced Cytokine Modulation: Effectively inhibits the production of pro-inflammatory mediators such as PGE2 and IL-6, significantly reducing skin redness and environmental sensitivity.
• Urban Pollution Defense: Strengthens the skin’s biological resilience against airborne pollutants and heavy metals by preventing the activation of the Aryl Hydrocarbon Receptor (AhR) pathway.
• Preventative Anti-Aging: Protects structural proteins by inhibiting UV-induced Matrix Metalloproteinases (MMPs), thereby preventing premature photo-aging and loss of elasticity.
• Applications: High-performance anti-blue light serums, urban defense mists, daily protective moisturizers, and soothing treatments for stressed or reactive skin.

Formulation Guidelines

• Recommended Dosage: 0.1% – 1.0% (effective even at low concentrations).
• Incorporation: Lipophilic nature. Must be pre-dissolved in a suitable solvent system such as Propanediol or Ethanol before being added to the oil phase of an emulsion or into anhydrous systems.
• pH Stability: Best maintained in formulations with a pH range of 4.5 – 6.5. High pH may lead to oxidation and color shifts.
• Compatibility/Stability Notes: Light-sensitive; finished products should be packaged in opaque or UV-protected containers. Highly compatible with other lipophilic antioxidants like Vitamin E.
• Synergy: Combine with Bifida Ferment Lysate for advanced DNA-level repair or with Squalane for a skin-identical carrier system that enhances the transdermal delivery of this flavonoid.