Pantothenic Acid (B5)

Product Description

Our high-purity Pantothenic Acid (Vitamin B5) is produced under ISO-aligned controls with batch COA traceability, offering cosmetic formulators direct factory supply and flexible bulk volumes from kilogram to tonne scale.

As a coenzyme A (CoA) precursor, pantothenate drives acyl-transfer steps in fatty acid synthesis and stratum corneum lipid renewal—pathways tied to barrier recovery, lower transepidermal water loss, and post-procedure comfort in aqueous serums and emulsions.

Unlike D-panthenol pro-vitamin forms, this INCI-listed free acid suits neutral water-phase systems where formulators want direct B5 activity for sensitive-skin, repair, and scalp-care lines without retinoid-like irritation.

Product Specification

• INCI Name: Pantothenic Acid
• CAS No.: 79-83-4
• Appearance: White to off-white crystalline powder (Typical)
• Solubility: Freely soluble in water; sparingly soluble in ethanol (Typical)
• Suggested pH: 6.0–7.5 in aqueous systems (Typical)
• Assay Method: HPLC or alkalimetric titration (Typical)
• Shelf Life: 24 months sealed, below 25°C (Typical)
• Standard Packaging: 1 kg / 25 kg
• Storage: Keep sealed, protected from light and moisture (Typical)
• Regulatory Status: Listed in CosIng as Pantothenic Acid; INCI recognized
• Quality & Testing: Typical COA covers assay, heavy metals, and microbial limits
• Compliance Note: For cosmetic use only; avoid prolonged storage below pH 4.5 where hydrolytic degradation may occur

Key Benefits & Applications

Pantothenic Acid supports barrier-centric cosmetic claims through CoA-linked lipid metabolism, hydration, and calming activity for repair and sensitive-skin portfolios.

• Skin Barrier Repair: CoA-dependent fatty acid synthesis helps restore stratum corneum lipids in compromised or over-exfoliated skin.
• Wound Healing Support: Supports epithelial recovery kinetics relevant to post-treatment gels and recovery balms.
• Deep Hydration: Humectant activity binds aqueous moisture in water-based toners and lightweight essences.
• TEWL Control: Reinforces barrier function to limit transepidermal water loss in dry-climate moisturizers.
• Anti-Inflammatory Soothing: Calms visible redness in sensitive-skin and after-sun care without steroid-like actives.

Formulation Guidelines

Use pantothenic acid in neutral aqueous systems; screen emulsifier compatibility and salt form solubility for stable cosmetic-grade delivery.

• Suggested use level: 0.5–5% w/w in serums, creams, and scalp tonics (Typical).
• Processing: Add to aqueous phase at 40–50°C; pre-dissolve in water or propylene glycol for clear gels.
• pH window: Maintain 5.5–7.0; avoid prolonged exposure below pH 4.5 to limit hydrolytic degradation.
• Compatibility: Works with humectants and niacinamide; add strong acids after cool-down when possible.
• Preservation: Not a standalone preservative; pair with broad-spectrum systems in water-rich bases.
• Synergy: Pair Niacinamide at 2–5% with pantothenate in barrier-repair serums for stacked NAD+ and CoA cofactor support.