Phospholipase

Product Description

Phospholipase is a sophisticated enzyme that functions as a high-technology "delivery system enhancer." Unlike actives that provide a direct skin benefit, Phospholipase's role is to optimize the formulation itself. Its highly specific action hydrolyzes phospholipids, the key components of the skin's lipid barrier. By gently and temporarily modifying this barrier, it creates pathways that significantly enhance the penetration and bioavailability of other, often expensive, active ingredients (like peptides, retinol, or growth factors). For B2B manufacturers, Phospholipase is a strategic tool for creating "booster" serums and next-generation delivery systems, ensuring that key actives reach their target for maximum, measurable efficacy.

Product Uses

Phospholipase is a high-cost, high-performance active intended for premium, state-of-the-art anti-aging and skin-defense formulations. It is specifically designed to be co-formulated with Glutathione (GSH) and/or Glutathione Peroxidase (GPx) to create a complete, rechargeable antioxidant system. Its primary applications are in advanced "total defense" serums, prestige anti-aging creams, and intensive barrier repair products designed to combat chronic environmental stress, UV-induced damage, and inflammation. It is the ultimate ingredient for brands competing at the highest level of biotechnological efficacy.

Formulation Suggestions

As a bioactive enzyme, Phospholipase must be incorporated during the cool-down phase, with temperatures kept below 45°C (113°F). Its activity is highly pH-dependent, with an optimal range often near neutral (pH 6.0 - 7.5). **Crucially, many phospholipases (especially A2) are calcium-dependent.** Their activity may be significantly enhanced by the presence of calcium ions (e.g., from Calcium Chloride) in the formulation, or inhibited by strong chelating agents (like EDTA). Encapsulation is often recommended to stabilize the enzyme until the point of application. Our recommendations are for reference only; please follow the advice of your formulator for actual production.

Product Specification

• INCI Name: Phospholipase
• Synonyms: Lecithinase, Phosphatidase
• CAS No.: 9001-84-7
• Molecular Formula: Complex Polypeptide
• Appearance: White to light yellow powder
• Purity: ≥98%
• Solubility: Soluble in water.
• Stability: Stable as dry powder. Heat sensitive (avoid >50°C). Activity is often calcium-dependent.
• Properties: Enzyme, Penetration Enhancer, Bio-converter, Delivery System
• Origin: China