Pyridoxine (B6)

Product Description

Our high-purity Pyridoxine HCl is produced under GMP-aligned cosmetic-grade standards with lot-wise COA documentation and direct factory supply for scalable bulk procurement.

Pyridoxine (vitamin B6) functions as a water-soluble coenzyme in amino-acid and protein metabolism, supporting keratinocyte renewal, mild antioxidant defense, and scalp comfort in leave-on aqueous skincare systems.

Compared with lipophilic retinoid actives, this CosIng-listed PYRIDOXINE HCl enables formulators to add B6 conditioning to water-phase essences without emulsifier-heavy delivery systems.

Product Specification

• INCI Name: PYRIDOXINE HCl
• CAS No.: 58-56-0
• Appearance: White to light-yellow crystalline powder (Typical)
• Solubility: Freely soluble in water; soluble in alcohol (Typical)
• Suggested pH: 4.0–6.5 for stable aqueous systems (Typical)
• Assay Method: HPLC or UV spectrophotometry (Typical)
• Shelf Life: 24 months sealed, stored below 25°C (Typical)
• Standard Packaging: 1 kg / 25 kg foil-lined drums
• Storage: Cool, dry place; protect from light and moisture
• Regulatory Status: Listed in CosIng as PYRIDOXINE HCl; INCI recognized
• Quality & Testing: Typical COA includes assay, heavy metals, and microbial limits
• Compliance Note: For cosmetic use only; not for injectable or oral supplement claims

Key Benefits & Applications

Pyridoxine HCl delivers water-phase B6 activity for formulators building antioxidant, metabolic-support, and scalp-comfort leave-on systems.

• Supports pyridoxine-dependent antioxidant pathways that moderate reactive oxygen species in water-based daily serums.
• Delivers B6 cofactor activity aligned with amino-acid metabolism in revitalizing essences at 0.05–0.5% w/w.
• Encourages keratinocyte protein turnover signaling for smoother facial texture in lightweight toner matrices.
• Relieves dry, tight scalp feel when incorporated into leave-on hair tonics alongside humectants and mild surfactants.
• Calms visibly stressed skin in multi-vitamin toner systems without elevating formula irritation potential.

Formulation Guidelines

Pyridoxine HCl fits water-phase B6 dosing for serums, scalp tonics, and multi-vitamin essences within typical cosmetic concentration windows.

• Use 0.01–0.5% w/w in the water phase of serums, essences, or scalp tonics.
• Pre-dissolve in water or hydroalcoholic pre-mix; add below 45°C to reduce hydrolysis.
• Keep formula pH 4.0–6.5; avoid strong oxidizing agents and prolonged high-alkaline conditions.
• Compatible with common humectants; test stability with ascorbic acid and copper salts before scale-up.
• Synergy: Layer Niacinamide beneath pyridoxine in multi-B serums to align amino-acid metabolism with barrier lipid repair.