Retinol

Product Description

Green Stone Swiss supplies high-purity Retinol (Vitamin A, CAS 68-26-8) through direct factory channels with batch HPLC documentation for cosmetic OEM manufacturers developing night treatment and anti-aging product lines.

Retinol binds cellular retinoic acid receptors, upregulating keratinocyte turnover and collagen synthesis signaling while addressing photo-aging appearance in lipophilic topical matrices.

Formulators specify retinol at controlled percentages in night serums, encapsulated emulsions, and PM-only treatment lines where vitamin A remains the benchmark active for visible wrinkle and texture improvement positioning.

Product Specification

• INCI Name: Retinol
• CAS No.: 68-26-8
• Appearance: Yellow to orange crystalline powder or pale yellow oil solution
• Particle Size: Micronized crystals for dispersion (Typical); encapsulated grades on request
• Solubility: Soluble in oils and ethanol; insoluble in water
• Suggested pH: Stable pH 5.0–6.5 in emulsions (Typical); avoid high alkali
• Assay Method: HPLC assay for all-trans retinol content (Typical)
• Shelf Life: 24 months sealed, −20°C to 2–8°C dark (Typical)
• Standard Packaging: 100 g / 1 kg amber glass; nitrogen-flushed foil bag
• Storage: −20°C or 2–8°C, dark, sealed; minimize oxygen and light exposure
• Regulatory Status: Listed in INCI; follow SCCS and regional retinol concentration guidance
• Quality & Testing: Typical COA: HPLC assay, all-trans content, peroxides, heavy metals
• Compliance Note: For cosmetic use only; PM-use labeling advised; verify local retinol limits before export

Key Benefits & Applications

Retinol delivers multi-pathway anti-aging and cell-renewal activity in night-use leave-on skincare at controlled concentrations.

• Retinoic Pathway Activation: Binds RAR receptors to accelerate visible skin renewal in PM anti-aging serums.
• Wrinkle Appearance Reduction: Supports dermal matrix remodeling appearance at 0.1–0.3% in night creams.
• Collagen Synthesis Support: Upregulates collagen I and III synthesis signaling in mature-skin treatment lines.
• Photo-Damage Defense: Addresses photo-aging appearance from prior UV exposure in recovery night formulas.
• Keratinocyte Turnover: Promotes desquamation and texture refinement in retinol resurfacing serums.

Formulation Guidelines

PM-only positioning recommended; use encapsulation or nitrogen processing for stability.

• Recommended use level: 0.05–0.3% face serums; 0.01–0.05% eye area (Typical)
• Optimal formula pH: pH 5.0–6.5 in O/W emulsions; buffer near 5.5–6.0
• Processing: Add to oil phase under nitrogen below 35°C; avoid prolonged heat and light
• Compatibility: Pair with ceramides and panthenol; separate from strong acids and direct L-AA in same leave-on
• Caution: Photosensitizing—mandate SPF AM use; introduce gradually; avoid pregnancy-use positioning
• Synergy: Boost night tolerance by adding Ceramide NP at 0.5–1.0% alongside retinol in barrier-support PM emulsions.