Serratiopeptidase

Product Description

Serratiopeptidase is a high-performance metalloprotease enzyme with powerful, targeted anti-inflammatory properties. Unlike exfoliating enzymes (like papain) that target surface keratin, Serratiopeptidase works as a "biological clean-up" agent deep within irritated tissue. Its unique function is to hydrolyze non-living protein-based debris, such as fibrin and bradykinin, which are the byproducts of inflammation that cause redness, swelling, and discomfort. This selective action clears the pathway for healing without harming living cells. For B2B manufacturers, this makes Serratiopeptidase a premier, high-tech active for developing sophisticated soothing solutions for problem skin.

Product Uses

This enzyme's potent anti-inflammatory and "debris-clearing" action makes it a strategic ingredient for advanced therapeutic formulations. It is a cornerstone active for **acne and blemish-prone skin** products, such as spot treatments and clearing serums. By dissolving inflammatory proteins within the pore, it helps to rapidly reduce the visible redness and swelling of a blemish. It is also ideal for **post-procedure** recovery creams and **sensitive skin** formulations, where it works to calm irritation and accelerate the skin's natural healing process by removing protein waste.

Formulation Suggestions

Serratiopeptidase is a bioactive enzyme and must be added during the cool-down phase (below 50°C / 122°F). It performs optimally in a neutral to slightly alkaline pH range (pH 7.0 - 9.0). **Crucially, as a metalloenzyme, its activity is zinc-dependent.** Formulators should avoid high concentrations of strong chelating agents (e.g., EDTA), which can bind to its zinc cofactor and deactivate the enzyme. For maximum shelf life, anhydrous (water-free) powder systems are ideal. Our recommendations are for reference only; please follow the advice of your formulator for actual production.

Product Specification

• INCI Name: Serratiopeptidase
• Synonyms: Serrapeptase, Serralysin, Serratia Peptidase
• CAS No.: 37312-62-2
• Molecular Formula: Metalloenzyme
• Appearance: White to off-white powder
• Purity: ≥98%
• Solubility: Soluble in water, insoluble in ethanol.
• Stability: Stable as dry powder. Heat sensitive (avoid >55°C). Optimal activity at neutral to alkaline pH (7.0-9.0).
• Properties: Enzyme, Proteolytic, Anti-inflammatory, Soothing, Healing Support
• Origin: China