Tanshinone IIA

Product Description

Tanshinone IIA is a high-purity, potent diterpene quinone isolated from the revered TCM herb Danshen (*Salvia miltiorrhiza*). It represents the core "cooling" and purifying power of this traditional remedy, now validated by modern science for skincare. Its key advantage lies in its strong, targeted action against key factors of acne: inhibiting *P. acnes* bacteria, significantly reducing inflammation, and helping to regulate sebum production. For formulators developing high-performance, TCM-inspired solutions for oily, congested, and particularly inflammatory acne-prone skin, Tanshinone IIA is a premier active choice.

Product Uses

This potent active is ideal for high-efficacy, targeted dermo-cosmetic formulations:

• Problem Skin: The perfect hero ingredient for anti-acne spot treatments, clarifying serums, and purifying masks specifically targeting red, inflamed blemishes.
• Oily Skin Control: Used in mattifying lotions and toners to help regulate sebum production.
• Soothing Formulations (Niche): Incorporated into specialized calming products leveraging its potent anti-inflammatory action.

Formulation Suggestions

The recommended dosage is typically 0.05-0.5%. Tanshinone IIA is an oil-soluble powder. It must be pre-dissolved in the oil phase, often requiring gentle heating (50-70°C), or in a suitable solvent like ethanol/glycols before incorporation. **Formulation Alert:** This ingredient has a strong red color and is sensitive to light and oxidation. It will tint the final product. Robust antioxidant systems (e.g., Vitamin E) and chelators are recommended. **Opaque, airless packaging is mandatory.** Microencapsulated forms can mitigate color and stability issues.

Our advice is for reference only. Please follow the recommendations of your formulator for

Product Specification

• INCI Name: Tanshinone IIA
• Synonyms: Danshen Triterpene Quinone, Tanshinone II
• CAS No.: 568-72-9
• Molecular Formula: C₁₉H₁₈O₃
• Appearance: Cherry-red crystalline powder
• Purity: ≥98%
• Solubility: Soluble in oils, ethanol, acetone, chloroform. Insoluble in water.
• Stability: Sensitive to light and oxidation. Requires protection in formulation and packaging.
• Properties: A potent diterpene quinone from Salvia miltiorrhiza. Provides strong anti-inflammatory, antimicrobial (anti-P. acnes), sebum-regulating, and antioxidant benefits. Particularly effective for inflammatory acne.
• Origin: China