Alanine/Histidine/Lysine Polypeptide Copper Hcl

Product Description

We supply high-purity Alanine/Histidine/Lysine Polypeptide Copper HCl (AHK-Cu) from controlled peptide synthesis lines, with HPLC batch release plus COA and SDS available upon request for B2B buyers.

The Ala-His-Lys·Cu2+ complex delivers bioavailable copper to dermal papilla cells, supporting follicle proliferation and Type I collagen upregulation versus glycine-based Copper Tripeptide-1 analogs.

Scalp-as-skin and firming brands specify AHK-Cu for dual hair-density and ECM remodeling claims in aqueous leave-on serums at microdose use levels.

Product Specification

• INCI Name: Alanine/Histidine/Lysine Polypeptide Copper HCl
• CAS No.: 682809-81-0
• Sequence: Ala-His-Lys·Cu2+ (AHK-Cu)
• Molecular Formula: C15H24ClCuN6O4 (Typical)
• Purity (HPLC): ≥98% (Typical)
• Appearance: Blue to purple fine powder
• Particle Size: 80–120 mesh (Suggested, Typical)
• Suggested pH: 5.0–7.0 in finished formulas (Typical)
• Assay Method: HPLC for peptide purity; Cu content by AAS/ICP (Typical)
• Shelf Life: 24 months sealed at 2–8°C, protected from light (Typical)
• Standard Packaging: 1 g / 10 g / 100 g / 1 kg
• Regulatory Status: INCI listed; CosIng-indexed cosmetic ingredient (verify market rules)
• Quality & Testing: HPLC ≥98%; heavy metals & microbial limits per COA (Typical)
• Compliance Note: For cosmetic use only; not for drug or injectable claims

Key Benefits & Applications

AHK-Cu copper peptide supports follicle signaling and dermal matrix renewal in scalp and facial leave-on formulas.

• Hair Follicle Activation: Stimulates dermal papilla proliferation to support hair density in scalp serums and tonics.
• Collagen Upregulation: Promotes Type I collagen synthesis for a firmer dermal matrix in matrix-support leave-ons.
• Firming Support: Reinforces ECM remodeling pathways that improve perceived skin firmness in face and neck creams.
• Antioxidant Copper Delivery: Supplies chelated Cu2+ that aids ROS balance in stressed scalp and facial skin.
• Tissue Remodeling: Supports cosmetic tissue-remodeling cues useful in post-procedure recovery gels and masks.

Formulation Guidelines

Add AHK-Cu in the cool-down water phase; protect the copper–peptide chelate from heat, strong chelators, and oxidizers.

• Recommended use level: 0.01–0.1% w/w in leave-on scalp tonics and facial firming serums (Typical).
• Optimal formula pH: Maintain 5.0–7.0 to preserve Cu2+ chelation stability in aqueous systems.
• Processing: Predissolve in water below 40°C after emulsion cool-down; avoid prolonged heating.
• Compatibility: Avoid EDTA and strong oxidizers that may displace copper from the AHK complex.
• Synergy: Formulators often co-add Copper Tripeptide-1 at 0.05% to stack follicle and dermal ECM pathways in scalp serums.