Dextranase

Product Description

Dextranase is a high-specificity enzyme that functions as a powerful anti-biofilm agent, primarily for the B2B oral care market. Its sole function is to hydrolyze dextran—a sticky polysaccharide that acts as the "glue" for dental plaque (biofilm) created by *Streptococcus mutans*. Unlike abrasive agents that physically scrub plaque, Dextranase works biologically, dissolving the biofilm's structural matrix. This "bio-solution" makes it a cornerstone ingredient for manufacturers developing sophisticated, science-backed enzyme toothpastes. It offers a gentle yet highly effective mechanism for plaque control and cavity prevention, appealing to consumers seeking advanced, non-abrasive dental care.

Product Uses

The primary and most established application for Dextranase is as a key functional active in **oral care** formulations. It is the powerhouse ingredient in high-performance "anti-plaque" and "biofilm-control" **toothpastes**, where it works synergistically with fluoride and cleansing agents. It is also formulated into therapeutic **mouthwashes** and oral rinses designed to reduce plaque buildup and malodor. For manufacturers, it is the go-to ingredient for adding a clinically-proven, biotechnological advantage to a premium dental care line, targeting the root cause of plaque.

Formulation Suggestions

Dextranase is a protein enzyme and is sensitive to heat. It must be incorporated during the cool-down phase of the formulation, at temperatures below 50°C (122°F). It exhibits optimal activity and stability in a slightly acidic environment, with a final product pH of 5.0 to 6.5 being ideal. For comprehensive antimicrobial and plaque-control benefits, it is frequently co-formulated with the Lactoperoxidase (LPO) system (Lactoperoxidase + Glucose Oxidase). Our recommendations are for reference only; please follow the advice of your formulator for actual production.

Product Specification

• INCI Name: Dextranase
• Synonyms: Dextran hydrolase, (1->6)-alpha-D-glucan 6-glucanohydrolase
• CAS No.: 9025-70-1
• Molecular Formula: Complex Polypeptide
• Appearance: White to light yellow powder
• Purity: ≥98%
• Solubility: Soluble in water, insoluble in ethanol.
• Stability: Stable as dry powder. Optimal activity at pH 5.0-6.5. Heat sensitive (avoid >60°C).
• Properties: Enzyme, Biofilm-degrading, Anti-plaque, Oral Care
• Origin: China