Isoniacinamide

Product Description

Green Stone Swiss supplies high-purity Isoniacinamide manufactured under strict GMP-aligned quality systems, ensuring consistent batch-to-batch performance for professional cosmetic and personal care brands worldwide. Our direct factory supply model delivers reliable bulk quantities with full technical documentation and free sample support.

Isoniacinamide is the isomer of niacinamide used as a water-soluble conditioning active in tone-evening leave-on care. It is not niacinamide and should be specified separately on the COA. The material is a white crystalline powder that dissolves in water.

Essences and daily fluids continue to call for this INCI when a vitamin B3 isomer other than niacinamide is required. Cosmetic-grade Isoniacinamide is a practical bulk active when the assay distinguishes it from niacinamide.

Product Specification

• INCI Name: Isoniacinamide
• CAS No.: 1453-82-3
• Molecular Formula: C₆H₆N₂O
• Molecular Weight: 122.12 Da
• Appearance: White crystalline powder
• Purity: Typical ≥98%
• Solubility: Soluble in water
• Suggested pH: 5.0–7.0 in aqueous systems
• Storage: Store in a cool, dry place; protect from moisture

Key Benefits & Applications

Isoniacinamide is a water-soluble vitamin B3 isomer used in tone-evening leave-on systems.

• Used in essences that specify this isomer rather than niacinamide
• Dissolves in the water phase of fluids and gel creams
• Supports daily formulas aimed at uneven tone
• Pairs with ferulic acid in an antioxidant chassis
• Typical use level: 0.5–2.0% in leave-on formulations

Formulation Guidelines

Follow these guidelines to dissolve Isoniacinamide in the water phase.

• Suggested Use Level: Typical 0.5–2.0% in the finished formula
• pH Range: Suggested 5.0–7.0
• Addition: Dissolve in water during cool-down, below 40°C
• Stability: Confirm the isomer assay so the lot is not niacinamide
• Combine with Ferulic Acid when an oil-soluble antioxidant is needed in the same chassis.