Lipase

Product Description

Lipase is a high-efficacy enzyme that specializes in the hydrolysis of lipids (fats and oils). In cosmetics, it functions as a "biological degreaser," offering a unique and gentle mechanism for controlling excess sebum. Unlike harsh surfactants or irritating acids (like BHA), Lipase works by selectively breaking down triglycerides—the main components of skin oil—into more manageable fatty acids and glycerol. This targeted action makes it a strategic ingredient for B2B manufacturers developing sophisticated, next-generation solutions for oily and combination skin. It addresses the root cause of shine, blackheads, and congestion without compromising the skin barrier, making it ideal for "oily-sensitive" skin types.

Product Uses

Lipase's sebum-degrading ability makes it a prime active for a range of problem-skin formulations. It is exceptionally effective in "deep-pore" enzyme cleansers (both powder and gel) and clarifying clay masks, where it dissolves hardened sebum plugs (blackheads). It is also a key ingredient for oily skin serums and mattifying moisturizers, helping to control shine throughout the day. Furthermore, its efficacy extends to advanced **scalp care**, where it is used in shampoos and treatments to break down the excess sebum associated with oily scalps and seborrheic dermatitis, which can contribute to irritation and hair loss.

Formulation Suggestions

As a bioactive enzyme, Lipase is sensitive to heat and should always be incorporated during the cool-down phase of formulation, at temperatures below 45°C (113°F). Its optimal activity is typically in the neutral to slightly alkaline pH range (pH 7.0 - 9.0), making it suitable for many cleansing systems but challenging for acid-based formulas. It is most stable in anhydrous (water-free) powder formats. In aqueous solutions, stability can be a challenge and may require a specialized buffer or stabilization system. Avoid co-formulation with strong surfactants or solvents that can denature the enzyme. Our recommendations are for reference only; please follow the advice of your formulator for actual production.

Product Specification

• INCI Name: Lipase
• Synonyms: Triacylglycerol lipase, Steapsin
• CAS No.: 9001-62-1
• Molecular Formula: Complex Polypeptide
• Appearance: White to light yellow powder
• Purity: ≥98%
• Solubility: Soluble in water, insoluble in ethanol.
• Stability: Stable as dry powder. Optimal activity at neutral to slightly alkaline pH (7.0-9.0). Heat sensitive (avoid >60°C).
• Properties: Enzyme, Sebum-control, Cleansing, Lipolytic (Lipid-degrading)
• Origin: China