Palmitamide

Product Description

Palmitamide is a fatty acid amide derived from palmitic acid, widely used in cosmetic formulations for its emollient, skin-conditioning, and sensory modification properties.

From a molecular perspective, Palmitamide integrates into lipid matrix structures of the stratum corneum, supporting barrier flexibility and reducing transepidermal water loss through hydrophobic interaction with intercellular lipids.

With increasing demand for biomimetic lipid systems, Palmitamide is positioned as a functional ingredient for barrier-repair skincare, texture optimization, and enhanced skin feel systems.

Product Specification

• INCI Name: Palmitamide
• CAS No.: 629-76-5
• Appearance: White to off-white powder
• Solubility: Insoluble in water, soluble in oils and emulsifiers
• Suggested pH: 4.5–7.5
• Molecular Type: Fatty acid amide
• Storage: Store in cool, dry, sealed environment away from light
• Purity: ≥98% (Suggested)

Key Benefits & Applications

Palmitamide delivers multi-functional skin conditioning benefits through lipid-mimetic integration and barrier-support mechanisms.

• Lipid Barrier Support: Enhances stratum corneum lipid organization and structural integrity.
• TEWL Control: Reduces transepidermal water loss via hydrophobic lipid reinforcement.
• Skin Conditioning: Improves skin smoothness, softness, and sensory comfort.
• Texture Optimization: Enhances formulation spreadability and after-feel performance.

• Applications: Barrier repair creams
• Applications: Moisturizing emulsions
• Applications: Sensitive skin formulations
• Applications: Lipid-replenishing skincare systems

Formulation Guidelines

Palmitamide is suitable for lipid-based and emulsion systems requiring enhanced skin feel and barrier reinforcement.

• Suggested Use Level: 0.1–2.0%
• Processing Recommendation: Add in oil phase with heating to 70–80°C for complete dissolution
• Compatibility: Ceramides, cholesterol, fatty alcohols, squalane
• Stability: Stable under normal cosmetic formulation conditions
• Synergy: Combine with Cholesterol to enhance stratum corneum lipid bilayer organization and support intercellular lipid lamellar structure integrity, improving barrier cohesion, TEWL reduction, and long-term skin moisturization stability.