Cholesterol

Product Description

As a dedicated wholesale supplier of skin-identical lipids and barrier-repair actives, GSS offers High Purity Cholesterol at factory-direct prices for the global cosmetic industry. This high-purity crystalline lipid is an indispensable structural component of the human stratum corneum, making up approximately 25% of the intercellular lipid matrix. It plays a critical role in regulating barrier fluidity, stabilizing the lipid bilayer, and ensuring the structural integrity of the "brick-and-mortar" skin model. Our Cholesterol is optimized for high-performance dermo-cosmetic applications, providing a reliable bulk supply for formulations targeting intensive skin restoration and physiological repair.

Product Specification

• INCI Name: Cholesterol
• Chemical Name: Cholest-5-en-3β-ol
• Synonyms: Cholesterin, 3β-Hydroxy-5-cholestene
• CAS No.: 57-88-5
• Molecular Formula: C27H46O
• Molecular Weight: 386.65 g/mol
• Appearance: White to off-white crystalline powder or flakes
• Purity (Assay): ≥98.0% (GC/HPLC)
• Solubility: Soluble in hot oils, esters, and organic solvents; insoluble in water
• Melting Point: Approximately 148°C
• Grade: Cosmetic Grade (High Purity)
• Origin: China (Direct Factory Supply)

Key Benefits & Applications

• Physiological Barrier Reconstruction: Essential for re-establishing the lamellar lipid structure in the stratum corneum, particularly in skin compromised by aging, harsh surfactants, or environmental stress.
• TEWL Mitigation: By reinforcing the lipid bilayer, it significantly reduces Transepidermal Water Loss (TEWL), maintaining deep-tissue hydration.
• Biomimetic Conditioning: Enhances skin elasticity and suppleness by replenishing the natural lipid levels that decline with age.
• Inflammation Modulation: Helps soothe sensitive and atopic-prone skin by fortifying the physical shield against external allergens and irritants.
• Applications: Formulated in high-end restorative night creams, post-procedure ointments, barrier-repair serums, and specialized care for mature or extremely dry skin.

Formulation Guidelines

• Recommended Dosage: 0.1% – 2.0% (Typically used at 0.5% in standard barrier-repair systems).
• Incorporation: Must be added to the oil phase. Due to its high melting point (approx. 148°C), it is recommended to co-melt with other lipids or pre-dissolve in a compatible high-temp carrier oil/ester to ensure complete integration.
• pH Stability: Highly stable across a wide pH range (3.0 – 9.0).
• Compatibility/Stability Notes: Requires thorough homogenization during the emulsification process. Controlled cooling rates are imperative to prevent recrystallization, which can lead to a "gritty" texture in the final emulsion.
• Synergy: Combine with Ceramide NP and Stearic Acid in a 1:3:1 or 1:1:1 molar ratio to achieve the "Golden Ratio" for physiological barrier repair, or with Phytosphingosine to stimulate endogenous lipid synthesis.