Glycerophosphocholine

Product Description

Green Stone Swiss manufactures high-purity Glycerophosphocholine under GMP-aligned quality controls for consistent batch identity and reliable bulk availability. Our direct factory supply model supports global cosmetic brands with full technical documentation, COA/TDS packages, and free sample evaluation for formulation screening.

Glycerophosphocholine (also known as Alpha-GPC / L-alpha-glycerylphosphorylcholine) is a water-soluble phospholipid metabolite and choline donor that participates in phosphatidylcholine pathways linked to cell-membrane integrity. As a CosIng-recognized skin conditioning agent, it supports hydration comfort, barrier-oriented lipid metabolism, and aqueous leave-on systems where formulators need a compatible, non-oily phospholipid precursor.

Demand continues to rise for science-led moisturizing and barrier-care actives in serums, essences, eye care, and body firming emulsions. High-purity Glycerophosphocholine offers a clear INCI story and strong formulation flexibility for premium skincare lines seeking phospholipid-based skin conditioning performance with stable factory-direct supply.

Product Specification

• INCI Name: Glycerophosphocholine
• CAS No.: 28319-77-9
• Molecular Formula: C₈H₂₀NO₆P
• Molecular Weight: 257.22 Da
• Appearance: White to off-white crystalline powder
• Purity: ≥98% (HPLC, Typical)
• Solubility: Highly soluble in water; suitable for aqueous phase incorporation
• Suggested pH: Typical 5.0–7.0 in finished systems
• Storage: Store cool and dry in a tightly closed container; protect from moisture

Key Benefits & Applications

Glycerophosphocholine is a phospholipid-pathway skin conditioning active used to support hydration comfort and barrier-oriented leave-on formulas.

• Provides water-soluble phospholipid precursor support for cell-membrane integrity narratives
• Supports deep hydration and moisture retention in aqueous serums and emulsions
• Helps reinforce barrier-care positioning through choline/phospholipid metabolism relevance
• Compatible with humectant systems for long-lasting moisturizing leave-on products
• Suitable for facial care, eye-area care, essences, sheet masks, and body conditioning creams
• Typical use level: 0.1–1.0% in leave-on formulations (confirm with TDS for project design)

Formulation Guidelines

Use these guidelines to incorporate Glycerophosphocholine efficiently into stable aqueous cosmetic systems.

• Suggested Use Level: Typical 0.1–1.0% in final formulation; body systems may use higher Typical levels—validate per TDS
• pH Range: Suggested 5.0–7.0 for best aqueous stability
• Addition: Predissolve fully in the water phase; add during cool-down preferably below 40°C
• Compatibility: Compatible with most humectants and mild emulsifiers; protect hygroscopic powder from moisture during handling
• Stability: Avoid prolonged extreme heat and strongly oxidizing environments; store finished goods away from humidity
• Combine with Phosphatidylcholine for complementary phospholipid pathway support in barrier and hydration systems.