A brief that only says “add FGF” is still not a sample request. sh-Polypeptide-11 is a defined INCI: a single-chain recombinant human peptide for acidic fibroblast growth factor 1 (aFGF / FGF-1), sold here as a white to off-white lyophilized powder with HPLC purity 99% or higher.
It is not rh-Polypeptide-11, not basic FGF (sh-Polypeptide-1), and not EGF (sh-Oligopeptide-1). Clear that gate before you ask for a price: sh-Polypeptide-11 INCI: Match sh, Not rh or 11 Alone.
What the INCI is locking
INCI definitions circulating from industry mirrors describe sh-Polypeptide-11 as a single chain produced by fermentation in E. coli. The starting gene is a synthesized copy of the human gene that codes for acidic fibroblast growth factor 1, used as written or adapted to the host. The chain contains a maximum of 155 amino acids and may include disulfide bonds or glycosylation. The amino acids are the 20 standard ones.
For purchasing, write the INCI you will put on the label: sh-Polypeptide-11. Ask for a COA that shows the same name and the HPLC or assay result for that lot. Do not fill the line with a growth-factor nickname alone.
What “for skin” is deciding
Searches for sh-Polypeptide-11 for skin and benefits are placement questions. The recorded cosmetic function is skin conditioning. Formulators put the powder into water-based serums and creams when the brief asks for this acidic FGF peptide as a discrete active line.
That role is a formula-placement decision. It is not a wound-treatment instruction, and a finished cream still has to earn any firmness claim on its own data. Keep branded clinical percentages with the named commercial grade that published them.
People also search this INCI with hair. The function on record is still skin conditioning. A hair base uses the same powder only at the level and pH on the TDS for that grade. The search does not add a separate hair-result specification.
How this powder goes into water
This grade is water-soluble. The product specification says the aqueous solution is stable at pH 5.0–7.0, and that extreme pH and high temperature should be avoided. Add the peptide during cool-down, below 40°C, at the temperature written on the TDS. Storage on that specification is 2–8°C, protected from light and moisture.
Suggested use on the product page is 1.0–10.0%, depending on active concentration and formulation requirements. Read that band against the concentration of the grade you buy. A diluted trade solution and a neat lyophilized powder do not share the same weighing math. Set the pilot percent from the TDS of the drum or vial you receive, then confirm stability in your own base.
What not to substitute silently
Three mix-ups show up on the same RFQ thread.
rh-Polypeptide-11 also points to acidic FGF-1, but the INCI definitions split sh and rh by gene source. This site has no rh-Polypeptide-11 page. An order for the sh INCI is not filled by the rh INCI.
sh-Polypeptide-1 is the synthesized-gene peptide for basic fibroblast growth factor (FGF-2). Different factor, different amino-acid ceiling in the definition.
sh-Oligopeptide-1 is the epidermal growth factor peptide on this site. The product page notes it can sit beside sh-Polypeptide-11 in an epidermal-plus-dermal concept—that is still two SKUs and two COAs. The full naming split is in sh-Polypeptide-11 INCI.
What to send before the first sample ships
Put these lines in the message to the supplier:
- INCI sh-Polypeptide-11
- Target identity: acidic fibroblast growth factor 1 (aFGF / FGF-1)
- HPLC or assay target for the grade you will weigh (≥99% if that is your brief)
- Cool-down addition below 40°C and pH window 5.0–7.0 for your process
- Storage expectation 2–8°C if your logistics need it stated
- Bench-sample pack size, plus COA, SDS, and TDS with the shipment
- A CAS only when that COA prints one
Batch documents and a sample are available from the product page. Match the sample COA to the specification you wrote, then scale. A clear sh-Polypeptide-11 line usually returns documents and a quote; a vague “FGF powder” line usually returns clarifying questions first.
