A brief that only says “probiotic” or “ferment” is still not a sample request. Lacticaseibacillus Rhamnosus Ferment Lysate is the lysate from a fermentation with Lacticaseibacillus rhamnosus. The cells are broken open. What goes into the drum is cellular material and metabolites—a postbiotic preparation—not a living culture you can plate as a probiotic count.
How that name sits next to the older Lactobacillus ferment lysate INCI, and how a lysate differs from a filtrate, is in Lysate vs Filtrate and the Old Lactobacillus Name.
What the INCI is locking
The Cosmetic Ingredient Review groups Lactobacillus ferment lysates as skin-conditioning agents. The species behind this grade was formerly called Lactobacillus rhamnosus; NCBI Taxonomy now uses Lacticaseibacillus rhamnosus. CIR’s 2025 assessment of four Lactobacillus ferment ingredients, including the lysate, concluded they are safe in cosmetics in the present practices of use and concentration. In that survey, Lactobacillus Ferment Lysate was reported in eye lotions at up to 4.6%. That figure is for the genus-level INCI, not an automatic dose for this species-specific grade.
The grade on this site is typically a cloudy to pale yellow liquid, water-soluble, with suggested finished pH often around 4.0–6.0. CAS is not universally assigned; confirm any CAS only on the commercial grade’s documents—do not invent one.
What “for skin” is deciding
Searches for this lysate in skin care are placement questions. Buyers put it in water-phase serums, creams, toners, and masks when the brief asks for a microbiome-oriented or soothing postbiotic from this organism. That is the formula job. Do not brief it as a live probiotic, and do not brief it as a preservative that replaces the preservation assessment of the finished product.
A supplier study summarized by CIR used a cream containing this species’ ferment lysate and reported less redness and dryness. That is one cream study, not a result you can copy onto another base. Keep branded clinical percentages with the named grade that published them.
How this liquid goes into the formula
Add it to the aqueous phase under gentle mixing. For emulsions, add after emulsification on cool-down, preferably below 40°C, so the fermentation-derived components are not cooked. Confirm temperature and pH against the TDS of the lot you buy.
The product page notes pairing with Sodium Hyaluronate Crosspolymer when the brief wants complementary hydration. That remains a second purchase line. Bifida Ferment Lysate is another lysate on this site from a different organism—do not silently substitute it for Lacticaseibacillus rhamnosus.
What not to substitute silently
A filtrate is not a lysate. A live culture is not this postbiotic drum. A COA that only says “Lactobacillus ferment lysate” has not locked the species. Clear that naming fork in Lysate vs Filtrate and the Old Lactobacillus Name.
What to send before the first sample ships
Put these lines in the message to the supplier:
- INCI Lacticaseibacillus Rhamnosus Ferment Lysate
- Organism Lacticaseibacillus rhamnosus, preparation = lysate (not filtrate, not live culture)
- Marker or composition the COA reports; CAS only if that grade prints one
- Cool-down addition and pH window for your process
- Bench-sample pack size, plus COA, SDS, and TDS with the shipment
Batch documents and a sample are available from the product page. Match the sample to the specification, then scale.
