Epsilon-Polylysine

Product Description

As a dedicated wholesale supplier of functional bio-polymers and natural actives, GSS offers High Purity Epsilon-Polylysine (ε-Polylysine) at factory-direct prices. Produced through the specialized fermentation of Streptomyces albulus, this cationic homopolymer serves as a robust "Clean Beauty" alternative to traditional synthetic preservatives. Its unique mechanism of action involves strong electrostatic adsorption to microbial cell membranes, leading to structural disruption and a potent bacteriostatic effect. Our ε-Polylysine provides a strategic solution for formulating preservative-free or natural-origin systems without compromising shelf-life stability, meeting the rigorous standards of global B2B procurement for safe, biological formulation components.

Product Specification

• INCI Name: Epsilon-Polylysine (or Polyepsilon-lysine)
• Chemical Name: Poly-L-lysine,Poly-epsilon-lysine,epsilon-PL, EPL
• Synonyms: ε-Polylysine, Poly-epsilon-L-lysine
• CAS No.: 28211-04-3
• Molecular Formula: 6H122n
• Appearance: White to pale yellow hygroscopic powder
• Purity (Assay): ≥98.0% (Active content)
• Solubility: Highly stable in aqueous solution; slightly soluble in ethanol
• Stability: Heat stable up to 120°C; active across a wide pH range (2.0–9.0)
• Grade: Cosmetic Grade
• Origin: China (Direct Factory Supply)

Key Benefits & Applications

• Broad-Spectrum Antimicrobial Activity: Provides highly effective inhibition against Gram-positive and Gram-negative bacteria, yeasts, and molds, ensuring comprehensive product protection.
• Microbiome-Targeted Acne Care: Specifically inhibits Cutibacterium acnes, making it a powerful active for clarifying toners and specialized anti-acne treatments.
• Cationic Substantivity: Due to its positive charge, it binds effectively to the hair and skin, offering mild conditioning benefits and scalp-soothing properties in hair care systems.
• Clean Beauty Compliant: Ideal for formulations avoiding parabens, phenoxyethanol, and formaldehyde releasers, supporting "Natural" and "Preservative-Free" marketing claims.
• Applications: High-end facial serums, anti-dandruff scalp treatments, sensitive skin lotions, and biodegradable wet wipes.

Formulation Guidelines

• Recommended Dosage: 0.01% – 0.5% (typically 0.1% as a preservative booster).
• Incorporation: Highly water-soluble. Can be added to the aqueous phase at any manufacturing stage; heat stable up to 80°C during standard emulsification.
• pH Stability: Maintains maximum antimicrobial efficacy between pH 2.0 and 9.0.
• Compatibility/Stability Notes: As a cationic polymer, it is incompatible with anionic surfactants (SLS, SLES) and anionic thickeners (Carbomer, Xanthan Gum), which may result in precipitation. Use non-ionic (HEC) or cationic (Cationic Guar) thickeners for optimal stability.
• Synergy: Combine with Phytosphingosine for a complete microbiome-balancing and barrier-repair system, or with Totarol for an advanced, multi-target natural antibacterial shield in acne-prone skin formulations.